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Hyperhomocysteinemia in Type 2 Diabetes [Medeniyet Med J]
Medeniyet Med J. 2001; 16(4): 213-215

Hyperhomocysteinemia in Type 2 Diabetes

Gonca Tamer
SSK Kartal Hospital, Internal Medicine Clinic, Istanbul

Homocysteine is a toxic aminoacid formed by demetilation of methionine taken in normal diet. Hyperhomocysteinemia is a risk factor for cardiovascular and cerebrovascular diseases
and also thromboemboli. Hyperhomocysteinemia is more frequent in type 2 diabetes than normal population.

In this study, plasma levels of homocysteine were investigated in two groups; a patient-group formed out of 32 type 2 diabetic patients and a control group of 32 healthy volunteers. The plasma homocystein level was found significantly higher in type 2 diabetics than in control group (p<0.001).

Keywords: Type 2 diabetes, homocysteine, microalbuminuria


Tip 2 Diabette Hiperhomosisteinemi

Gonca Tamer
SSK Kartal Hastanesi İç Hastalıkları Kliniği, İstanbul

Homosistein; diyetle alınan methioninin demetilasyonundan elde edilen toksik bir aminoasittir. Hiperhomosisteineminin, tromboemboli, kardiyovasküler ve serebrovasküler hastalıklar için bir risk faktörü olduğu ve tip 2 diabette normal topluma göre daha yüksek olduğu bildirilmiştir.

Bu çalışmada tip 2 diabetli 32 hasta ile 32 kişilik sağlıklı kontrol grubunda plazma homosistein düzeyleri araştırılmış, tip 2 diabetlilerde plazma homosistein düzeyi, kontrol grubuna göre çok ileri düzeyde anlamlı olarak yüksek bulunmuştur (p<0.001).

Anahtar Kelimeler: Tip 2 diabet, homosistein, mikroalbuminüri


Gonca Tamer. Hyperhomocysteinemia in Type 2 Diabetes. Medeniyet Med J. 2001; 16(4): 213-215

Corresponding Author: Gonca Tamer, Türkiye


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