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Volume : 35 Issue : 1 Year : 2020



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Nasal Plasmablastic Lymphoma in an HIV-Negative Immunocompetent Patient [Medeniyet Med J]
Medeniyet Med J. 2020; 35(1): 71-74 | DOI: 10.5222/MMJ.2020.45389  

Nasal Plasmablastic Lymphoma in an HIV-Negative Immunocompetent Patient

Nadhirah Mohd Shakri1, Salina Husain1, Farah Dayana Zahedi1, Geok Chin Tan2
1Department Of Otorhinolaryngology - Head & Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Kuala Lumpur, Malaysia
2Department Of Pathology, Universiti Kebangsaan Malaysia Medical Centre

Plasmablastic lymphoma (PBL) is a rare and aggressive variant of diffuse large B-cell lymphoma predominantly in oral cavity of human immunodeficiency virus (HIV)-positive male patients or immunosuppressive hosts. HIV-negative PBL in immunocompetent patients has not been extensively reported. We reported an unusual case of sinonasal PBL which occurs in an HIV-negative and immunocompetent female patient. She underwent endoscopic removal of the tumor and completed 6 cycles of chemotherapy (hyperfractionated-CVAD). Positron-emission tomography scan (PET-scan) 18 months post treatment showed no evidence of tumour recurrence.

Keywords: non-Hodgkin lymphomas, plasmablastic lymphoma, sinonasal


Nadhirah Mohd Shakri, Salina Husain, Farah Dayana Zahedi, Geok Chin Tan. Nasal Plasmablastic Lymphoma in an HIV-Negative Immunocompetent Patient. Medeniyet Med J. 2020; 35(1): 71-74

Corresponding Author: Salina Husain, Malaysia


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