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A Case report, imitating metastatic liver cancer radiologicaly: Fasciola Hepatica [Medeniyet Med J]
Medeniyet Med J. 2006; 21(4): 197-199

A Case report, imitating metastatic liver cancer radiologicaly: Fasciola Hepatica

Zeki Aydın1, Ahmet Akın1, Didem Aydın1, Muharrem Koçar1, Aylin Ege Gül2, Rahmi Irmak1, İlyas Tuncer3, Mustafa Yaylacı1
1Dr. Lutfi Kirdar Kartal Training and Research Hospital, II. Internal Medicine, Istanbul
2Dr. Lutfi Kirdar Kartal Training and Research Hospital, Department of Pathology, Istanbul
3Goztepe Training and Research Hospital, Gastroentereoloj Clinic, Istanbul

Fasciola hepatica, a zoonotic liver fluke, can also cause disease in humans. Common symptoms are epigastric pain, upper abdominal pain and malaise. Fever and arthralgia are common in acute fascioliasis. Eosinophilia is the predominant laboratory finding, especially in patients with the acute form of the disease. Diagnosis is not easy, as physicians rarely encounter this disease. A 25 years old man was admitted to the clinic with severe right upper abdominal pain. There was a two-month history of mild jaundince, trembling and fever. Abnormal laboratory findings were as follows: alanin aminotranspherase: 77U/L, aspartat aminotranspherase: 55U/L, alkalen phosphatase: 648 U/L (N: 11-49) gamma glutamyl transpeptidase: 142 U/L (N: 11-49). Abdomen ultrasonography and magnetic resonance imaging (MRI) revealed multiple, 1,5 cm sized lesions of which biggest was 1.5 cm, compatible with metastasis. Other systems were normal. Since 40 % eosinophilias were present in peripheral blood, fecal examination
was performed but no parasite and parasite eggs were detected. Liver biopsy that was performed for metastatic liver cancer suspicion revealed fasciola hepatica. Fasciola
hepatica antibody result was 1: 80 positive. The patient was administered triclabendazol 10 mg/kg for fasciola hepatica diagnosis. After 3 months, the symptoms were improved and laboratory and imaging results returned completely back to normal. Patients with eosinophilia and abdominal pain should be evaluated for F. hepatica infestation by parasitological, radiological and serological tests.

Keywords: Fasciola hepatica, metastatic liver cancer, eosinophilia


Radyolojik olarak metastatik karaciğer tümörü ile karışan bir olgu: Fasciola hepatica

Zeki Aydın1, Ahmet Akın1, Didem Aydın1, Muharrem Koçar1, Aylin Ege Gül2, Rahmi Irmak1, İlyas Tuncer3, Mustafa Yaylacı1
1Dr. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi, II. Dahiliye Kliniği, İstanbul
2Dr. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi, Patoloji Kliniği, İstanbul
3Göztepe Eğitim ve Araştırma Hastanesi, Gastroentereoloji Kliniği, İstanbul

Anahtar Kelimeler: Fasciola hepatica, metastatik karaciğer kanseri, eosinofili


Zeki Aydın, Ahmet Akın, Didem Aydın, Muharrem Koçar, Aylin Ege Gül, Rahmi Irmak, İlyas Tuncer, Mustafa Yaylacı. A Case report, imitating metastatic liver cancer radiologicaly: Fasciola Hepatica. Medeniyet Med J. 2006; 21(4): 197-199

Corresponding Author: Zeki Aydın, Türkiye


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