Home | Contact
     ISSN 2149-2042
     e-ISSN 2149-4606
 
 
 
Volume : 35 Issue : 1 Year : 2020



Current Issue Archive Popular Articles Ahead of Print




Index














Membership




Applications



 
Intravitreal triamcinolone and pars plana vitrectomy for diabetic macular edema that persists laser treatment [Medeniyet Med J]
Medeniyet Med J. 2005; 20(4): 197-199

Intravitreal triamcinolone and pars plana vitrectomy for diabetic macular edema that persists laser treatment

Hasan Horoz, Esma Duru, Hasan Erbil
Goztepe Training and Research Hospital, Eye Clinic, Istanbul

INTRODUCTION: To ascertain the efficacy of combined surgical and pharmacological treatment for refractory diffuse diabetic macular edema.
METHODS: 11 patients with clinically significant macular edema (CSME) resistant to prior laser treatment were prospectively evaluated with optic cohererence tomography (OCT). All patients underwent vitrectomy, removal of attached vitreous cortex without peeling of the ILM and, at the end of the operation, an injection of 4 mg of triamcinolone into the vitreous cavity. They were followed up for a median 36 weeks.
RESULTS: A marked reduction in median retinal thickness could be detected from baseline: 502±141 μm, at 1 month: 231±44 μm and 3month: 234±92 μm. At 6 months the median retinal thickness was decreased compared to baseline: 410±170 μm.
DISCUSSION AND CONCLUSION: The rapid and benefical effect of intraocular steroid in diffuz diabetic macular edema that persists after laser treatment was confirmed. Simultaneous removal of the vitreous in diabetic eyes appears to reduce the need for re-injections of triamcinolone.

Keywords: Macular edema, triamcinolone, vitrectomy


Laser tedavisine dirençli diyabetik makula ödeminde pars plana vitrektomi ve intravitreal triamsinolon

Hasan Horoz, Esma Duru, Hasan Erbil
Göztepe Eğitim ve Araştırma Hastanesi, Göz Kliniği, İstanbul

GİRİŞ ve AMAÇ: Diffüz diyabetik makula ödeminde pars plana vitrektomi (PPV) ve intravitreal triamsinolon uygulamasının makula kalınlığına etkisini araştırmak.
YÖNTEM ve GEREÇLER: Laser fotokoagülasyona rağmen düzelmeyen diffüz diyabetik makula ödemli 11 hasta optik koherens tomografi ile prospektif olarak değerlendirildi. Tüm hastalara iç limitan membran (ILM) soyulmadan arka hiyaloid dekole edilip vitreus korteksi alınarak pars plana vitrektomi ve operasyon bitiminde 4 mg intravitreal triamsinolon uygulandı. Hastalar ortalama 36 hafta takip edildiler.
BULGULAR: Ortalama retinal kalınlıkta belirgin azalma gözlendi; preop: 502±141 μm, 1. ay: 231±44 μm ve 3. ay: 234±92 μm. 6. ayda ortalama retinal kalınlık preop kalınlığa göre daha azdı: 410 μm.
TARTIŞMA ve SONUÇ: Bu çalışmada laser tedavisine dirençli diffüz diyabetik makula ödeminde göziçi steroidlerin hızlı ve olumlu etkisi kanıtlanmaktadır. Aynı anda vitre korteksinin alınması triamsinolonun tekrar enjeksiyon ihtiyacını azaltıyor gözükmektedir.

Anahtar Kelimeler: Makular ödem, triamsinolon, vitrektomi


Hasan Horoz, Esma Duru, Hasan Erbil. Intravitreal triamcinolone and pars plana vitrectomy for diabetic macular edema that persists laser treatment. Medeniyet Med J. 2005; 20(4): 197-199

Corresponding Author: Hasan Horoz, Türkiye


TOOLS
Full Text PDF
Print
Download citation
RIS
EndNote
BibTex
Medlars
Procite
Reference Manager
Share with email
Share
Send email to author

Similar articles
PubMed
Google Scholar





 

  Copyright © 2019 MEDJ All Rights Reserved