Comparing 5-year Outcomes of Aorta-Coronary Bypass Surgery and Percutaneous Coronary Intervention with New-Generation Drug-Eluting Stents in Non-Diabetic and Multivessel Acute Coronary Syndrome Patients with Intermediate Syntax ScoreFirdovsi İbrahimov1, Yusuf Yılmaz2, Isfandiyar İsmayilov1, Kamran Musayev3, Ogtay (Oktay) Musayev4, Shahana Alasgarli4, Shafa Shahbazova4, Mehriban İsgenderova4, Tofig Jahangirov5
1Department of Cardiology, Azerbaijan Medical University, Baku, Azerbaijan
2Department of Cardiology, Istanbul Medeniyet University, Istanbul, Turkey
3Department of Cardiovascular Surgery, Central Hospital of Baku, Baku, Azerbaijan
4Department of Cardiology, Central Hospital of Baku, Baku, Azerbaijan
5Department of Cardiology, J. Abdullayevs Research Institute of Cardiology, Baku, Azerbaijan
Objectives: Our main objective was to determine the difference between patients undergoing CABG and PCI (with new-generation drug-eluting stents) who were non-diabetic during the course of a multi-vessel acute coronary syndrome (ACS) and intermediate SYNTAX score.Keywords: PCI, CABG, non-diabetic, stent, mortality, acute coronary syndrome,
Methods: Between 2012 and 2014, we evaluated retrospectively 1011 non-diabetic patients with ACS in a single center. The follow-up of patients was done up to 5-years. Death associated with all causes, cardiac death, myocardial infarction, stroke, revascularization and stent thrombosis were recorded accordingly.
Results: 516 (%51) patients were included in the PCI group and 495 patients (%49) were in the CABG group. Stroke occurrence (0.8% in the PCI group and 2.6% in the CABG group, p = 0.022), repeated revascularization requirement (13.6% of the PCI group and 8.1% in the CABG group, p = 0.005) and the MACE percentage (20.3% in the PCI group, 14.5% in the CABG group, p = 0.015) were statistically significant between two groups. However, there was no statistical significance between two groups in terms of primary endpoints including death, MI, and stroke (10.9% in the PCI group and 8.3% in the CABG group, p = 0.165) and all-cause mortality (%6.2 in the PCI group, %4.7 in the CABG group, p=0.298).
Conclusion: There was no difference in all-cause mortality and myocardial infarction between the PCI and the CABG groups during a 5-year follow-up. Repeated revascularization was lower in the CABG group than the PCI group. In contrast, the stroke rates were higher in the CABG group.
Firdovsi İbrahimov, Yusuf Yılmaz, Isfandiyar İsmayilov, Kamran Musayev, Ogtay (Oktay) Musayev, Shahana Alasgarli, Shafa Shahbazova, Mehriban İsgenderova, Tofig Jahangirov. Comparing 5-year Outcomes of Aorta-Coronary Bypass Surgery and Percutaneous Coronary Intervention with New-Generation Drug-Eluting Stents in Non-Diabetic and Multivessel Acute Coronary Syndrome Patients with Intermediate Syntax Score. Medeniyet Med J. 2020; 35(2): 121-127
Corresponding Author: Firdovsi İbrahimov, Azerbaijan