Heart Failure and Renin-Angiotensin System

Heart failure is an inability of the heart to deliver blood at a rate commensurate with the requirements of the metabolizing tissues desbite normal cardiac filling pressures. Clinically
heart failure is a syndrome. ACE inhibitors reduce the symptoms and signs of this syndrome. We are to optimize treatment coverage of these patients, we must consider factors that inhibit prescription of ACE inhibitors. ACE inhibitors in patients with heart failure has been shown both in short and the long term to reduce systemic pressure and pulmonary
capillary wedge pressure, to reduce systemic vascular resistance and to increase cardiac output.

Keywords: Heart failure, renin, angiotensin, ACE inhibitors

Kalp Yetersizliği ve Renin-Anjiotensin Sistemi

Anahtar Kelimeler: Kalp yetersizliği, renin, anjiotensin, ACE inhibitörleri