Renal Tubular Acidosis with Hypokalaemic Paralysis and Nephrolitiasis

Hypokalaemic paralysis is a life-threatening clinical syndrome characterised clinically by hipokalaemia and acute systemic weakness. It represents a heterogeneous group of
disorders, most of them are familial. Sporadic cases are associated with numerous disorders including renal disorders, barium poisoning, hyperthyroidism, certain endocrinopathies and gastrointestinal potassium losses. Initial therapy of the
patient with hypokalaemic paralysis includes potassium replacement and search for underlying aetiology (1). The recurrent attacks with normal plasma potassium levels
between attacks distinguish periodic paralysis from other causes (2). The presence of type 1 RTA should be considered in any patient with a normal anion gap metabolic acidosis and an inappropriate high urine pH (3). The complications to renal tubular acidosis including hypokalaemic muscle paralysis or chronic muscle weakness, nephrolitiasis, and osteomalacia can be avoided if the diagnosis of renal tubular acidosis
is made and corrective alkali therapy is maintained (4).

Hipokalemik Paralizi ve Nefrolitiyazis ile Seyreden Bir Distal Renal Tubuler Asidoz