The hemolitic-uremic syndrome

The hemolitic-uremic syndrome (HUS) is the most common cause of acute renal failure in young children and the incidence is increasing. The syndrome is most common in children
under the age of 4 year. The onset is usually preceded by gastroenteritis (fever, vomiting, abdominal pain and diarrhea, which is often bloody) or less commonly, by an upper respiratory tract infection. This is followed in 5-10 days by the sudden onset of pallor, irritability, weakness, lethargy and oliguria. Physical examination may reveal dehydration, edema, petechiae, hepatosplenomegaly and marked irritability. The primer event in pathogenesis of the syndrome appears to be endothelial cell injury. Treatment is symptomatic. Plasmapheresis or the administration of fresh frozen plasma or both
are recomended. Long term observation is necessary to watch off late development of hypertension or chronic kidney disease. ‹n this report a case who was diagnosed HUS are presented. HÜS should be considered in differential diagnosis of acut begining anemia with renal failure signs.

Hemolitik Üremik Sendrom