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Histopathological evaluation of endometrial sampling in different age groups - 1374 cases [Medeniyet Med J]
Medeniyet Med J. 2017; 32(1): 26-32 | DOI: 10.5222/MMJ.2017.026  

Histopathological evaluation of endometrial sampling in different age groups - 1374 cases

Meltem Azatçam1, Eren Altun2, Akın Usta3
1Republic of Turkey Ministry of Health Lüleburgaz Steate Hospital, Medical Pathology
2Balıkesir University School of Medicine Department of Medical Pathology
3Balıkesir Univesity, School of Medicine, Department of Obstetrics and Gynecology

The aim of this study was to evaluate the relationship between
histopathological results and endometrial sampling and to identify
specific pathologies in different age groups. The histopathological
results of 1374 cases registered in our pathology archives,
in whom endometrial sampling was performed in our hospital for
various reasons between 2013 and 2014 were evaluated. Biopsy
indications included menometrorrhagia (80.5%), postmenopausal
bleeding (6.8%), myoma uteri (1.7%), cervical polyp (2.4%),
infertility (0.2%), and hyperplasia/malignancy (8.4%). Histopathological
diagnoses in order of frequency included endometrial
polyp (37.2%), proliferation/secretion/menstrual phase (29.3%),
irregular proliferative endometrium (8.4%), insufficient biopsy
material (8.4%), endometritis (5.8%), stroma-glandular breakdown
(4.2%), endometrial hyperplasia (4%), iatrogenic changes
(1.4%), atrophic endometrium (1.2%), and malignancy (0.1%).
Endometrial polyps were detected in 14 of 33 patients with cervical
polyps In endometrial samplings performed in patients in
whom hysterectomy was planned due to myoma uteri, the most
frequent diagnosis was a normal cyclic pattern (50%). In conclusion,
in the present study, the most frequent biopsy indications
of endometrial sampling were menometrorrhagia, and the most
frequent histopathological diagnosis was endometrial polyp. Endometrial
polyp was also identified concomitantly in endometrial
sampling of 14 out of 33 patients with cervical polyps. Thus, we
concluded that in patients with an initial diagnosis of cervical
polyp, the endometrium should also be evaluated.

Keywords: Endometrial sampling, menometrorrhagia, postmenopausal bleeding, cervical polyp


Endometriyal örneklerin farklı yaş gruplarında histopatolojik değerlendirmesi - 1374 olgu

Meltem Azatçam1, Eren Altun2, Akın Usta3
1T.C. Sağlık Bakanlığı Lüleburgaz Devlet Hastanesi Tıbbi Patoloji Laboratuvarı
2Balıkesir Üniversitesi Tıp Fakültesi Tıbbi Patoloji Anabilim dalı
3Balıkesir Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum Anabilim dalı

Bu çalışmanın amacı, endometriyal örneklemin histopatolojik sonuçlarla ilişkisini değerlendirmek ve farklı yaş gruplarındaki spesifik patolojileri tanımlamaktır.
Hastanemizde 2013-2014 yılları arasında çeşitli nedenlerle endometrial örnekleme yapılan patoloji arşivlerinde yer alan 1374 olgunun histopatolojik sonuçları değerlendirildi. Biyopsi endikasyonları; menometrorrhagia (% 80,5), postmenopozal kanama (% 6,8), myoma uteri (% 1,7), servikal polip (% 2,4), infertilite (% 0,2) ve hiperplazi-malignite (% 8.4) idi. Histopatolojik tanılar endometrial polip (% 37,2), proliferasyon / sekresyon / menstrüel faz (% 29,3), düzensiz çoğalma endometriyumu (% 8.4), yetersiz biyopsi materyali (% 8.4), endometrit (% 5.8) (% 4.2), iyatrojenik değişiklikler (% 1.4), atrofik endometrium (% 1.2), malignite (% 0.1) ve endometriyum hiperplazisi (% 4) izlendi. Servikal polip bulunan hastalardaki 33 endometriyal küretajın 14'ünde endometrial polip tespit edildi. Myoma uteri nedeniyle histerektomi planlanan olgularda yapılan endometriyal örneklemelerde en sık görülen normal siklik paterndi (% 50) idi. Çalışmamızda en sık görülen tanı endometrial polip olarak tanımlandı. Servikal polipin ön tanısı konan vakalarda endometriyumun da değerlendirilmesi gerektiği sonucuna varıldı.

Anahtar Kelimeler: Endometrial örnekleme, menometroraji, post menopozal kanama, cervikal polip


Meltem Azatçam, Eren Altun, Akın Usta. Histopathological evaluation of endometrial sampling in different age groups - 1374 cases. Medeniyet Med J. 2017; 32(1): 26-32

Corresponding Author: Eren Altun, Türkiye


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