Intoxication of diltiazem

Intoxications of calcium channel blocker which is used in lots of conditions such as hypertension, supraventriculer arrhythmias, angina pectoris; are more fatal than other cardiac drugs. In this study, we aimed to review the intoxications of calcium channel blockers because of a case. 34 years old male case was brought to emergency un›t, after three hours taking 120 diltiazem tablets( each of them is 60 miligram) for suicide. Acut renal failure occured after 24 hours in the patient having complete atrioventriculer block at the beginning. Cardiac rythm of the patient was normal in 27th hour. The patient who was taken hemodylasis twice in coronary care unit, was transported to the internal medicine service because of renal failure. Vasodilatation that occured because of the effects
in smooth muscle cells in calcium channel blockers overdose, gives rise to decreasing in cardiac output, hypotension and shock. Decreasing in organ perfusion can be concluded
with multi-organ disfunction. We wanted to point because of a case developing complete atrioventriculer block and renal failure,intoxications of calcium channel blocker is a condition having high mortality and morbidity, and it must be treated
fastly and aggresively.

Diltiazem intoksikasyonu