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Shift Work Association with Cardiovascular Diseases and Cancers among Healthcare Workers: A Literature Review [Medeniyet Med J]
Medeniyet Med J. 2019; 34(4): 387-395 | DOI: 10.5222/MMJ.2019.54775  

Shift Work Association with Cardiovascular Diseases and Cancers among Healthcare Workers: A Literature Review

Mainul Haque1, Adamu Yau2
1The Unit of Pharmacology, Faculty of Medicine and Defence Health, Universiti Pertahanan Nasional Malaysia (National Defence University of Malaysia), Kem Perdana Sungai Besi, 57000 Kuala Lumpur, Malaysia
2Department of Pharmacology and Therapeutics, Faculty of Pharmaceutical Sciences, Bayero University, Kano, Nigeria. Email: [email protected] Orcid ID: 0000-0003-2388-1085

The round-the-clock demands of healthcare services, coupled with the shortage of healthcare providers in many parts of the world have made shift work widespread among healthcare workers. Understanding how to mitigate adverse health effects associated with shift work is essential to health promotion, disease prevention, and quality of life. This comprehensive review aims to present evidence linking shift work with cardiovascular diseases and cancers among healthcare workers. Several studies demonstrated evidence of the association between long-term shift work exposure and the risk of cardiovascular diseases. The testimony about shift work-related adverse health effects has been on the rise among healthcare workers. Shift work disturbs circadian patterns and cardiopulmonary processes, leading to adverse health outcomes. Increasing prevalence of shift work in healthcare industries due to population expansion and public health threat of cancers call for investigation towards a better understanding of the underlying mechanism of shift work-induced diseases. Shift work period was considered in different studies using various criteria, resulting in inconsistent measurement definition leading to misclassification of the study population. There is a need for a more considerable and wholistic effort towards standardization of shift work definition, and conduct assessment to establish an actionable framework for intervention strategies.

Keywords: Shift Work, Rotating Shift Work, Cardiovascular, Cancers, Healthcare


Mainul Haque, Adamu Yau. Shift Work Association with Cardiovascular Diseases and Cancers among Healthcare Workers: A Literature Review. Medeniyet Med J. 2019; 34(4): 387-395

Corresponding Author: Mainul Haque, Malaysia


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