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Volume : 38 Issue : 4 Year : 2023



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Neuroendocrine carcinoma of the larynx [Medeniyet Med J]
Medeniyet Med J. 2004; 19(4): 253-254

Neuroendocrine carcinoma of the larynx

M. Hakan Karabulut, Aylin Ege Gül, Sibel Şensu, Dilek Yavuzer, Nimet Karadayı, Arif Şanlı
Dr. Lutfi Kirdar Kartal Training and Research Hospital, Department of Pathology, Istanbul

In this report, by reviewing the literature, we present a case of 70 year old male patient with the neuroendocrine carcinoma of the larynx which has been diagnosed and treated in our hospital.

Neuroendocrine carcinomas of the larynx are very rare tumors. These tumors can be seen as gray whitish or light brown masses varying in size from small polyps to extensive
lesions. Microscopically pleomorphism, mitotic activity and necrosis can be seen. Immunohistochemistry shows characteristic positive staining with chromogranin-A and neuron spesific enolase (NSE). Most of the cases are male and intense smokers. Clinical course is agressive due to extensive local lymphatic and distant metastases and mortality rate is 50 %.

Keywords: Neuroendocrine carcinoma, larynx, laryngectomy


Larenks’te nöroendokrin karsinom

M. Hakan Karabulut, Aylin Ege Gül, Sibel Şensu, Dilek Yavuzer, Nimet Karadayı, Arif Şanlı
Dr. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi, Patoloji Kliniği, İstanbul

Anahtar Kelimeler: Nöroendokrin karsinom, larenks, larenjektomi


M. Hakan Karabulut, Aylin Ege Gül, Sibel Şensu, Dilek Yavuzer, Nimet Karadayı, Arif Şanlı. Neuroendocrine carcinoma of the larynx. Medeniyet Med J. 2004; 19(4): 253-254

Corresponding Author: M. Hakan Karabulut, Türkiye


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