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Frequancy of type II diabetes mellitus, hyperlipidemia and obesity at nonalcoholic steatohepatit [Medeniyet Med J]
Medeniyet Med J. 2004; 19(2): 104-106

Frequancy of type II diabetes mellitus, hyperlipidemia and obesity at nonalcoholic steatohepatit

Ayşe Kubat Üzüm, Şebnem İzmir Güner
SSK Istanbul Training Hospital Internal Medicine Clinic, Istanbul

NASH (nonalcoholic steatohepatitis) is a frequently occuring asymptomatic clinicopathologic situation which is defined by the presence of histologic findings in the liver of patients who don’t consume alcohol where these findings are similar to fatty degeneration caused by alcohol.
In this study, we performed liver biopsy to the patients whose AST and ALT levels are increased 2-2.5 times. 33 patients (27 women, 6 men) who had steatohepatitis are included to the study. We aimed to find the frequency of obesity, diabetes mellitus and hyperlipidemia going with the steatohepatitis were included to the study. Average age was 48.9±2.1, average BMI was 32.47±3.6 kg/m2. The main value of total cholesterol
was 227.14±41.8, trigliseride was 164.59±84.7. According to the oral glucose tolerance test we found diabetes mellitus in 6 patients (% 18), impaired glucose tolerance in 8 patients (% 24).

Keywords: Nonalcoholic steatohepatit, diabetes mellitus, obesity, hyperlipidemia


Nonalkolik steatohepatitli olgularda tip II diabetes mellitus, hiperlipidemi ve obezite sıklığı

Ayşe Kubat Üzüm, Şebnem İzmir Güner
SSK İstanbul Eğitim Hastanesi İç Hastalıkları Kliniği, İstanbul

NASH (nonalkolik steatohepatit), alkol almayan kişilerin karaciğerinde alkole bağlı yağlanmaya benzer histolojik bulguların varlığı ile tanımlanan ve sıklıkla asemptomatik seyreden klinikopatolojik bir durumdur.
Bu çalışmada AST, ALT değerleri 2-2.5 kat artmış olan hastalara karaciğer biyopsisi yapıldı. 27’si kadın, 6’sı erkek toplam 33 hasta çalışmaya dahil edildi. Bu çalışmada steatohepatik
saptanan hastalarda obezite, diabetes mellitus ve hiperlipidemi sıklığını araştırdık. Ortalama yaş 48.9±2.1, ortalama VKİ (vücut kitle indeksi) 32.47±3.6 kg/m2, ortalama total kolesterol 227.14±41.8, trigliserid 164.59±84.7 olarak saptandı. Hastalarda diabetes mellitus ve bozulmuş glukoz toleransını saptamak için oral glukoz tolerans testi uyguladık. 6 hastada (% 18) diabetes mellitus, 8 hastada (% 24) bozulmuş glukoz toleransı saptadık.

Anahtar Kelimeler: Nonalkolik stetohepatit, diabetes mellitus, obezite, hiperlipidemi


Ayşe Kubat Üzüm, Şebnem İzmir Güner. Frequancy of type II diabetes mellitus, hyperlipidemia and obesity at nonalcoholic steatohepatit. Medeniyet Med J. 2004; 19(2): 104-106

Corresponding Author: Ayşe Kubat Üzüm, Türkiye


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