Value of split-bolus multidetector-row CT technique in the quantitative assessment of pancreatic enhancementMichele Scialpi1, Valeria Rondoni2, Nicola Recchia3, Francesco Barberini4, Paolo Baccari5, Maria Antonietta Mazzei6, Lucia Manganaro7, Luca Roncati8, Teresa Pusiol9, Barbara Palumbo101Michele Scialpi, MD, Department of Surgical and Biomedical Sciences, Division of Radiology 2 and Nuclear Medicine, Perugia University, S.Maria della Misericordia Hospital, S. Andrea delle Fratte, 06156 Perugia, Italy. E-mail: [email protected]; [email protected]
2Valeria Rondoni, MD, Department of Surgical and Biomedical Sciences, Division of Radiology 2 and Nuclear Medicine, Perugia University, S.Maria della Misericordia Hospital, S. Andrea delle Fratte, 06156 Perugia, Italy. E-mail: [email protected]
3Nicola Recchia, MD, Department of Surgical and Biomedical Sciences, Division of Radiology 2 and Nuclear Medicine, Perugia University, S.Maria della Misericordia Hospital, S. Andrea delle Fratte, 06156 Perugia, Italy. E-mail: [email protected]
4Francesco Barberini, MD, General and Oncological Surgery, Department of Surgical and Biomedical Sciences, S.Maria della Misericordia Hospital, S. Andrea delle Fratte 06156 Perugia, Italy. E-mail: [email protected]
5Paolo Baccari, MD, General Surgery, Department of Surgical and Biomedical Sciences, S.Maria della Misericordia Hospital, S. Andrea delle Fratte, 06156 Perugia, Italy. E-mail: [email protected]
6Maria Antonietta Mazzei MD, Departmen of Radiology, University Hospital of Siena, Viale Bracci, 53100 Siena, Italy.
7Lucia Manganaro, MD, Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, V.le Regina Elena 324, 00161 Rome, Italy.
8Luca Roncati, MD, Department of Diagnostic and Clinical Medicine and of Public Health, Section of Pathology University of Modena and Reggio Emilia, 41124 Modena, Italy.
9Teresa Pusiol, MD, Institute of Anatomic Pathology, Santa Maria del Carmine Hospital, Corso Verona 4, 38068 Rovereto (TN), Italy.
10Barbara Palumbo, MD, Division of Nuclear Medicine, Department of Surgical and Biomedical Sciences, S.Maria della Misericordia Hospital, S. Andrea delle Fratte, 06156 Perugia, Italy. E-mail: [email protected]
The aim is to assess quantitatively pancreatic enhancement by split-bolus intravenous injection of contrast material at 64-slice CT and radiation dose. Single-pass split-bolus MDCT of the chest and abdomen was performed in 37 patients without pancreatic disease. Regions of interest were evaluated in the pancreatic head, body and tail of the pancreas and mean attenuation values for pancreatic parenchymal phase (PPP) of the standard MDCT protocol and split-bolus were calculated. P <0.05 was considered statistically significant. Mean effective dose by split-bolus was measured. In all MDCT examinations split-bolus protocol allowed images of quality. Mean pancreatic enhancement was higher by split-bolus respect to pancreatic parenchymal phase of standard triphasic MDCT (131.35 HU ± 20.63 vs 126.1 HU ± 20.01). Reduction of dose was approximately 17%. In conclusion MDCT split-bolus protocol provides an optimal pancreatic enhancement, significantly greater than the enhancement of standard MDCT on PPP, involving an advantage for pancreatic tumors detection and staging. Keywords: Pancreas, Computed Tomography, oncology.
Pankreatik tutulumun kantitatif değerlendirilmesinde bölünmüş-bolus multidetektör-dizi BT tekniğinin değeriMichele Scialpi1, Valeria Rondoni2, Nicola Recchia3, Francesco Barberini4, Paolo Baccari5, Maria Antonietta Mazzei6, Lucia Manganaro7, Luca Roncati8, Teresa Pusiol9, Barbara Palumbo101Michele Scialpi, MD, Department of Surgical and Biomedical Sciences, Division of Radiology 2 and Nuclear Medicine, Perugia University, S.Maria della Misericordia Hospital, S. Andrea delle Fratte, 06156 Perugia, Italy. E-mail: [email protected]; [email protected]
2Valeria Rondoni, MD, Department of Surgical and Biomedical Sciences, Division of Radiology 2 and Nuclear Medicine, Perugia University, S.Maria della Misericordia Hospital, S. Andrea delle Fratte, 06156 Perugia, Italy. E-mail: [email protected]
3Nicola Recchia, MD, Department of Surgical and Biomedical Sciences, Division of Radiology 2 and Nuclear Medicine, Perugia University, S.Maria della Misericordia Hospital, S. Andrea delle Fratte, 06156 Perugia, Italy. E-mail: [email protected]
4Francesco Barberini, MD, General and Oncological Surgery, Department of Surgical and Biomedical Sciences, S.Maria della Misericordia Hospital, S. Andrea delle Fratte 06156 Perugia, Italy. E-mail: [email protected]
5Paolo Baccari, MD, General Surgery, Department of Surgical and Biomedical Sciences, S.Maria della Misericordia Hospital, S. Andrea delle Fratte, 06156 Perugia, Italy. E-mail: [email protected]
6Maria Antonietta Mazzei MD, Departmen of Radiology, University Hospital of Siena, Viale Bracci, 53100 Siena, Italy.
7Lucia Manganaro, MD, Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, V.le Regina Elena 324, 00161 Rome, Italy.
8Luca Roncati, MD, Department of Diagnostic and Clinical Medicine and of Public Health, Section of Pathology University of Modena and Reggio Emilia, 41124 Modena, Italy.
9Teresa Pusiol, MD, Institute of Anatomic Pathology, Santa Maria del Carmine Hospital, Corso Verona 4, 38068 Rovereto (TN), Italy.
10Barbara Palumbo, MD, Division of Nuclear Medicine, Department of Surgical and Biomedical Sciences, S.Maria della Misericordia Hospital, S. Andrea delle Fratte, 06156 Perugia, Italy. E-mail: [email protected]
Bu çalışmanın amacı, bölünmüş-bolus intravenöz kontrast madde kullanılarak yapılan 64 kesitli BT ile pankreatik artışı ve radyasyon
dozunu kantitatif olarak değerlendirmektir. Pankreatik bir hastalığı olmayan 37 hastaya (kadın: 18, erkek: 9, ortalama yaş: 66,1±14,2 yaş, aralık 17-80 yaş) göğüs ve abdomen tek geçiş bölünmüş-bolus MDBT uygulandı. Pankreas başı, gövdesi ve kuyruğundaki ilgili bölgeler değerlendirildi ve standart MDBT protokolünün pankreatik parankimal faz (PPF) için ortalama zayıflama değerleri ve bölünmüş-bolus dozları ölçüldü. P<0.05 değeri istatistiksel olarak anlamlı kabul edildi. Bölünmüş-bolus uygulamasının ortalama efektif dozu ölçüldü. Tüm MDBT incelemelerinde bölünmüş-bolus protokolü kaliteli görüntülere izin verdi. Ortalama panreatik artış PPF için bölünmüş-bolus uygulamasında standart trifazik MDBT e göre daha yüksekti (131,35 HU±20,63 vs 126.1 HU±20.01). bölünmüş bolus dozlu MDBT ‘de dozda azalma yaklaşık olarak %17 idi. Sonuç olarak, bölünmüş-bolus protokollü MDBT optimal pankreatik artış sağlar, pankreatik parankimal faz için özellikle standart MDBT değerlendirmesine göre önemli ölçüde üstünlük sağlar ve pankreas tümörlerinin belirlenmesi ve evrelemesi için avantajlıdır. Anahtar Kelimeler: Pankreas, multidetektör-dizi bilgisayarlı tomografi, radyasyon dozu, onkoloji
Michele Scialpi, Valeria Rondoni, Nicola Recchia, Francesco Barberini, Paolo Baccari, Maria Antonietta Mazzei, Lucia Manganaro, Luca Roncati, Teresa Pusiol, Barbara Palumbo. Value of split-bolus multidetector-row CT technique in the quantitative assessment of pancreatic enhancement. Medeniyet Med J. 2017; 32(3): 180-187
Corresponding Author: Michele Scialpi, Italy |
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